School of Medicine
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Research Engineer, Neurology
Bio Matt obtained a MS in mechanical engineering and PhD in neuroscience from the University of Illinois at Urbana-Champaign, and a BS/BA in mechanical engineering from the University of San Diego. His dissertation research primarily focused on improving gait initiation in people with Parkinson’s disease (PD) and freezing of gait (FOG) using a powered ankle foot orthosis. During his graduate career, he also worked on projects that examined the application of a powered ankle foot orthosis for gait assistance in persons with multiple sclerosis and perception vs. action coupling in firefighters wearing protective gear. He was awarded a MnDRIVE Neuromodulation Postdoctoral Fellowship in 2016 to develop quantitative measures of the mechanical and neurophysiological components of rigidity in PD. In 2017, he was awarded the Parkinson’s Study Group Mentored Clinical Research Award to evaluate an automated closed-looped algorithm to rapidly optimize deep brain stimulation settings for people with PD.
Kathleen Poston, MD, MS
Associate Professor of Neurology and, by courtesy, of Neurosurgery
Current Research and Scholarly Interests My research addresses one of the most devastating and poorly treated symptoms that can develop in people with Parkinson's disease - Dementia. We use multi-modal neuroimaging along with genetic and biological markers to understand the different underlying causes of dementia and to understand why dementia develops more quickly in some patients, but not others.
Edward F. and Irene Thiele Pimley Professor of Neurology and the Neurological Sciences
Current Research and Scholarly Interests Experiments examine
1)intrinsic properties of neuronal membranes; actions of neurotransmitters that regulate neocortical and thalamic excitability
2) chronic epileptogenesis following cortical injury; changes in intracortical connectivity and receptors;
3) effects of early injury and activity on cortical development/maldevelopment Electrophysiological, anatomical and pharmacological techniques employed.
4. prophylaxis of postraumatic epilepsy
5. Neocortical interneuronal function/modulation