School of Medicine
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Edward H. Wood, MD
Assistant Professor of Ophthalmology
Current Research and Scholarly Interests http://med.stanford.edu/woodlab.html
Edward H. Wood, MD is an assistant professor of ophthalmology practicing adult and pediatric vitreoretinal surgery at Stanford University School of Medicine. Dr. Wood engages in translational research with the goal of developing new therapies and approaches for patients without viable treatment options. He does so through leveraging the technologies of patient derived stem cells, optogenetics, and phenotypic drug screening in conjunction with active clinical research and surgical device development. Dr. Wood has filed numerous patents and founded several healthcare startups with the goal of improving patients’ quality of life. His research interests include regenerative medicine, drug discovery, and pediatric retinal disease with the ultimate goal of pursuing basic science discoveries with potential for impactful clinical translation. His research interests are significantly inspired by his patients, and he is driven towards not only delivering the highest quality of care currently available, but also in developing the future standard of care in the field of medical retina and vitreoretinal surgery.
John Fraser Wright
Professor (Research) of Pediatrics (Stem Cell Transplantation)
Bio J Fraser Wright, PhD
Dr. Wright received his PhD in 1989 from the University of Toronto (Biochemistry) for studies
characterizing the interaction of complement with IgM, and completed post-doctoral studies at INSERM
/ CENG Grenoble, France in molecular immunology focused on antigen processing and presentation. He
was awarded a CRCS/ MRC Scholarship, gaining faculty appointment at the University of Toronto. In
1996 he joined industry as a Scientist at Pasteur Sanofi, contributing there to the development of
vaccines and cancer immunotherapies, and subsequently as Director of Development and Clinical
Manufacturing at Avigen, a gene therapy company that pioneered AAV-based investigational gene
therapies for hemophilia and Parkinson’s disease. In 2004 he returned to academia, establishing and
directing the Clinical Vector Facility at the Center for Cellular and Molecular Therapeutics at Children’s
Hospital of Philadelphia, and gaining faculty appointment at the University of Pennsylvania Perelman
School of Medicine as professor of Pathology and Laboratory Medicine. Dr. Wright has contributed to
several clinical development programs in gene therapy, including for Luxturna and Kymriah, the first
gene therapies for a genetic (RPE65 deficiency) and non-genetic (CAR-T immunotherapy) disease,
respectively, approved in the United States, and for the first gene therapy clinical trial that delivered an
AAV-vectorized monoclonal antibody to human subjects for HIV passive immunity. He is a Co-founder of
Spark Therapeutics, serving there and subsequently at Axovant as Chief Technology Officer. In 2019 Dr.
Wright joined Stanford University as Professor of Pediatrics at The Center for Definitive and Curative
Medicine (CDCM). His research program aims to address key immunological barriers to gene therapy
through innovative approaches to viral vector design and generation, and to develop vectorized
antibodies for serious human diseases.
Albert Y. Wu, MD, PhD, FACS
Assistant Professor of Ophthalmology
Current Research and Scholarly Interests My translational research focuses on using autologous stem cells to recreate a patient’s ocular tissues for potential transplantation. We are generating tissue from induced pluripotent stem cells to treat limbal stem cell deficiency in patients who are bilaterally blind. By applying my background in molecular and cellular biology, stem cell biology, oculoplastic surgery, I hope to make regenerative medicine a reality for those suffering from orbital and ocular disease.
Current Research and Scholarly Interests I am interested in how the brain matures to control the bladder and external sphincter to achieve urinary continence. Using functional MRI of the brain, we are investigating if certain patterns of activity will predict which children will respond to therapy for incontinence.
Joseph C. Wu
Director, Stanford Cardiovascular Institute, Simon H. Stertzer, MD, Professor and Professor of Radiology
Current Research and Scholarly Interests Drug discovery, drug screening, and disease modeling using biobank of cardiac iPSC lines.
Associate Professor of Medicine (Endocrinology)
Current Research and Scholarly Interests My laboratory focuses on the pathways that regulate the differentiation of mesenchymal stem cells into the osteoblast and adipocyte lineages. We are also studying the role of osteoblasts in the hematopoietic and cancer niches in the bone marrow microenvironment.
Sean M. Wu
Associate Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Pediatrics
Current Research and Scholarly Interests My lab seeks to identify mechanisms regulating cardiac lineage commitment during embryonic development and the biology of cardiac progenitor cells in development and disease. We believe that by understanding the transcriptional and epigenetic basis of cardiomyocyte growth and differentiation, we can identify the most effective ways to repair diseased adult hearts. We employ mouse and human embryonic and induced pluripotent stem cells as well as rodents as our in vivo models for investigation.
Courtney Wusthoff, MD
Associate Professor of Neurology and, by courtesy, of Pediatrics (Neonatology)
Current Research and Scholarly Interests My projects focus on clinical research in newborns with, or at risk, for brain injury. I use EEG in at-risk neonates to better understand the underlying pathophysiology of risk factors that may lead to worse outcomes. I am particularly interested in neonatal seizures and how they may exacerbate perinatal brain injury with a goal to identify treatments that might protect the vulnerable brain. I am also interested in EEG in other pediatric populations, as well as medical ethics and global health.
Tony Wyss-Coray, PhD
D. H. Chen Professor II
Current Research and Scholarly Interests Use of genetic and molecular tools to dissect immune and inflammatory pathways in Alzheimer's and neurodegeneration.