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Gabrielle Devienne
Postdoctoral Scholar, Neurology and Neurological Sciences
Print Profile
Email Profile
Bio
Bio
Publications
Professional Education
Master of Science in Engr, E.S. Physiques Et Chimie Industrielles (2015)
Doctor of Science, Universite De Paris Vi (2019)
Licence, Universite de Paris V (Rene Descartes) (2013)
PhD, Sorbonne University, Paris, France, Neuroscience (2019)
Master, ESPCI & Paris Descartes University, France, Bioengineering and Innovation in Neurosciences (2015)
Bachelor, Paris Descartes University, France, Biomedical Sciences (2013)
Contact
devienne@stanford.edu
All Publications
Publications (5)
All Publications
(5)
Journal Articles
(5)
Presentations
(1)
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Research Interests
Our research goal is to understand how dynamics in neuronal circuits relate and constrain the representation of information and computations upon it. We adopt three synergistic strategies: First, we analyze neural circuit population recordings to better understand the relation between neural dynamics and behavior, Second, we theoretically explore the types of dynamics that could be associated with particular network computations. Third, we analyze the structural properties of neural circuits.
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Research Interests
We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.
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The Li Lab is primarily interested in RNA editing mediated by ADAR enzymes. We co-discovered that the major function of RNA editing is to label endogenous dsRNAs as "self" to avoid being recognized as "non-self" by MDA5, a host innate immune dsRNA sensor, leading us to pursue therapeutic applications in cancer, autoimmune diseases, and viral infection. The other major direction of the lab is to develop technologies to harness endogenous ADAR enzymes for site-specific transcriptome engineering.
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Publication Topics For This Person
Multiplex Polymerase Chain Reaction
Patch-Clamp Techniques
Reverse Transcription
Transcriptome