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School of Medicine

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  • Ronald W. Davis

    Ronald W. Davis

    Professor of Biochemistry and of Genetics

    Current Research and Scholarly Interests We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion.

  • Ning Deng

    Ning Deng

    Affiliate, Genetics

    Bio Ning Deng is a Senior Research Scientist in the Department of Genetics at Stanford University. She graduated with a Ph.D. in Biochemistry and Molecular Biology from the laboratory of Dr. Lin Li at the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, where her research focused on the Wnt signal pathway regulation and phosphoproteomics study. In 2008, Dr. Deng joined the research laboratory of Dr. Stanley N. Cohen at Stanford University, Genetics Department studying cancer drug-resistant gene Txr1 function. Later, she focused on the transcription elongation factor Supt4, which is required for certain expanded nucleotide repeats transcription such as CAG repeats in htt gene which causes Huntington's Disease. She set up and led a high-throughput screening for small molecules to interrupt transcription elongation complex and testing small molecules effect on lowering htt gene expression in iPSCs from Huntington's Disease patients. Now her interests expand to 1) exploration of global effects from Supt4 gene deficiency with NGS technologies; 2) Supt4's regulation on other nucleotide repeat diseases; 3) using microvesicles to deliver macromolecules to target cells.

  • Barbara L Dunn

    Barbara L Dunn

    Affiliate, Genetics

    Bio I'm a Senior Biocuration Scientist in the Department of Genetics at Stanford University, currently working with the Saccharomyces Genome Database in the laboratory of Dr. J. Michael Cherry. I received my A.B. in Botany at UC Berkeley, and my Ph.D. in Biological Chemistry at Harvard University, where I studied yeast telomeres in the laboratory of Dr. Jack Szostak. My recent bench research has focused on using whole-genome DNA and RNA sequencing, ChIP-Seq, array-CGH, and other ?omics? methods to broadly explore evolution in yeast, and particularly the genome structures and genome evolution of industrial yeasts (lager, ale, wine, ethanol, bread).

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