School of Medicine
Showing 21-30 of 37 Results
Yasuhiro Shudo, MD, PhD
Clinical Assistant Professor, Cardiothoracic Surgery
Bio Dr. Shudo is a board-certified cardiothoracic surgeon and clinical assistant professor in the Department of Cardiothoracic Surgery at Stanford University School of Medicine.
His clinical focus is the surgical treatment of end-stage cardiopulmonary failure, including heart transplant, heart-lung transplant, lung transplant, mechanical circulatory support (MCS), and extracorporeal membrane oxygenation (ECMO). He has published numerous landmark papers
Dr. Shudo also performs mitral valve repair/replacement (MVR), aortic valve replacement (AVR), complex valve surgery, coronary artery bypass graft (CABG) surgery, reoperative cardiac surgery, minimally invasive surgery, and transcatheter aortic valve replacement (TAVR).
Dr. Shudo is fully committed to innovative, comprehensive, and compassionate care for each patient he treats.
Julia Fridman Simard
Associate Professor of Epidemiology and Population Health and, by courtesy, of Medicine (Immunology & Rheumatology)
Bio Julia Fridman Simard, ScD, is an Associate Professor of Epidemiology & Population Health, and, by courtesy, of Medicine in Immunology and Rheumatology at Stanford University School of Medicine.
Dr. Simard earned her Masters and Doctorate of Science in Epidemiology degrees at the Harvard School of Public Health. During that time she trained with investigators at the Section of Clinical Sciences, Division of Rheumatology, Immunology, and Allergy at Brigham and Women?s Hospital and the Cardiovascular Epidemiology Research Unit at Beth Israel Deaconess Medical Center. In 2008, Dr. Simard relocated to Sweden to begin a Postdoctoral Fellowship in Clinical Epidemiology at the Karolinska Institutet in Stockholm. She became an Assistant Professor in their Clinical Epidemiology Unit in 2011, and was later honored with a Karolinska Institutet Teaching Award. Leveraging the population-based registers of Sweden, Dr. Simard initiated a national register linkage study to examine the utility of registers in Systemic Lupus Erythematosus (SLE) research and develop an extensive data repository for future epidemiologic investigations.
While maintaining a close collaboration with the Karolinska Institutet, she joined Stanford?s Epidemiology faculty as an Assistant Professor in 2013. Dr. Simard studies outcomes such as malignancy, stroke, infection, and mortality, in patients with systemic autoimmune rheumatic diseases, but her primary research focus has shifted to the intersection between reproductive epidemiology and rheumatic disease. In 2014 she was awarded a five-year K career development award from the NIH (NIAMS) to study maternal and fetal outcomes in systemic lupus pregnancy. This fueled a number of collaborations with colleagues at Stanford, throughout the US, and abroad, and a series of projects focused on the diagnosis of preeclampsia and associated risks in pregnant women with systemic lupus. Dr. Simard was recently awarded a Peter Joseph Pappas Research Grant from the Preeclampsia Foundation for her lab's work examining preeclampsia risk in high-risk populations, and a McCormick Faculty Award from Stanford Medicine to take important steps towards disentangling preeclampsia from lupus nephritis. In addition to these issues of misclassification in reproductive rheumatology questions, Dr. Simard's lab is also interested in how misclassification, missed opportunities, and misdiagnosis contribute to disparities in complex conditions such as SLE. In addition to methodologic issues around misclassification and bias and the largely clinical epi focus of her work, Dr. Simard's work examines social determinants of health and health disparities.
Current Research and Scholarly Interests Cholesterol in biological membranes; genetic mechanisms & cholesterol production
Stanford W. Ascherman, MD, FACS, Professor of Genetics
Current Research and Scholarly Interests Our laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states
Associate Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly Interests Pulmonary Arterial Hypertension
Pulmonary Vascular Remodeling
Modulation of BMP signaling
BMP signaling in health and disease in the right ventricle of the heart
"BMP signature" in blood as a biomarker
BMP signaling in neonatal chronic lung disease
Joshua M. Spin
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
Current Research and Scholarly Interests Dr. Spin began his research career studying the structural biology of low density lipoprotein, and has been augmenting his skills with intensive training in molecular biology techniques, particularly those involving high-throughput genetic expression profiling. He is especially interested in vascular smooth muscle cells, and the role of smooth muscle differentiation and phenotypic switching in development and vascular disease. His latest work has focused on the biology of aortic aneurysms.
Douglass M. and Nola Leishman Professor of Cardiovascular Disease
Current Research and Scholarly Interests The general research interest of this laboratory is the molecular basis of cell motility, with a current emphasis on power output by the human heart. We have three specific research interests, the molecular basis of energy transduction that leads to ATP-driven myosin movement on actin, the biochemical basis of the regulation of actin and myosin interaction and their assembly states, and the roles these proteins play in vivo, in cell movement, changes in cell shape and muscle contraction.
Marcia L. Stefanick, Ph.D.
Professor (Research) of Medicine (Stanford Prevention Research Center), of Obstetrics and Gynecology and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly Interests Marcia L. Stefanick, Ph.D is a Professor of Medicine Professor of Obstetrics and Gynecology, and by courtesy, Professor of Epidemiology and Population Health at Stanford University School of Medicine. Dr. Stefanick?s research focuses on chronic disease prevention (particularly, heart disease, breast cancer, osteoporosis, and dementia) in both women and men. She is currently the Principal Investigator the Women?s Health Initiative (WHI) Extension Study, having been the PI of the Stanford Clinical Center of the landmark WHI Clinical Trials and Observational Study since 1994 and Chair of the WHI Steering and Executive Committees from 1998-2011, as well as PI of the WHI Strong and Healthy (WHISH) Trial which is testing the hypothesis that a DHHS-based physical activity intervention, being delivered to a multi-ethnic cohort of about 24,000 WHI participants across the U.S., aged 68-99 when the trial started in 2015, will reduce major cardiovascular events over 8 years, compared to an equal number of ?usual activity? controls. Dr. Stefanick is also PI of the Osteoporotic Study of Men (MrOS) which is continuing to conduct clinical assessments of bone and body composition in survivors of an original cohort of nearly 6000 men aged 65 and over in 2001. As founding Director of the Stanford Women?s Health and Sex Differences in Medicine (WHSDM, ?wisdom?) Center, she plays a major role in promoting research and teaching on Sex and Gender in Human Physiology and Disease, Women?s Health and Queer Health and Medicine. Dr. Stefanick also plays major leadership roles at the Stanford School of Medicine, including as co-leader of the Population Sciences Program of the Stanford Cancer Institute, Stanford?s NCI-funded comprehensive cancer center.
Dr. Stefanick obtained her B.A. in biology from the University of Pennsylvania, Philadelphia, PA (1974), then pursued her interest in hormone and sex difference research at the Oregon Regional Primate Research Center, after which she obtained her PhD in Physiology at Stanford University, focusing on reproductive physiology and neuroendocrinology, with exercise physiology as a secondary focus. Her commitment to human research led to a post-doctoral fellowship in Cardiovascular Disease Prevention at the Stanford Prevention Research Center, which has been her academic home for nearly 40 years.