School of Medicine
Showing 1-3 of 3 Results
Victor G. Carrión
John A. Turner Endowed Professor for Child and Adolescent Psychiatry
Current Research and Scholarly Interests Examines the interplay between brain development and stress vulnerability via a multi-method approach that includes psychophysiology, neuroimaging, neuroendocrinology and phenomenology. Treatment development that focuses on individual and community-based interventions for stress related conditions in children and adolescents that experience traumatic stress.
Assistant Professor of Psychiatry and Behavioral Sciences
Current Research and Scholarly Interests The Chetty lab is interested in understanding the mechanisms underlying neurodevelopmental and psychiatric disorders, such as autism spectrum disorder and schizophrenia. In particular, our group has been investigating the mechanisms underlying brain overgrowth or undergrowth in these disorders using human induced pluripotent stem cell (hiPSC) technology. Changes in brain size often precede clinical symptoms, suggesting that understanding the underlying mechanisms regulating brain overgrowth or undergrowth could provide a window of opportunity for intervention or mitigation of symptoms.
Using hiPSCs from idiopathic patients as well as those with known genetic variations, we generate iPSC-derived cortical neural and oligodendroglial cells to investigate changes at the cellular, functional, and mechanistic levels using a broad range of techniques from RNA sequencing, genome editing, to functional assays in in vitro and in vivo models. The overarching goal of our research program is to identify novel therapeutic targets based on these mechanistic insights.