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Dr. Tsai is a Clinical Assistant Professor in the Division of Cardiothoracic Anesthesia and the Associate Program Director of the Adult Cardiothoracic Anesthesiology Fellowship. He graduated from the Perelman School of Medicine at the University of Pennsylvania and completed his anesthesiology residency at the Hospital of the University of Pennsylvania where he served as a Chief Resident. He completed an Adult Cardiothoracic Anesthesiology fellowship at Stanford, where he has remained on faculty. Dr. Tsai has special interests in medical student, resident, and fellow curriculum development and education, and the role of augmented reality technology in medical simulation.

Clinical Focus

  • Anesthesia
  • Cardiothoracic Anesthesia

Academic Appointments

  • Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine

Administrative Appointments

  • Associate Program Director, Adult Cardiothoracic Anesthesiology Fellowship (2020 - Present)
  • Clerkship Director, ANES 307A - Stanford Hospital Cardiovascular Anesthesia Clerkship (SUMC) (2019 - 2021)

Honors & Awards

  • Fellowship Clinical Teaching Award, Adult Cardiothoracic Anesthesiology Fellowship (2019)
  • Chief Resident, Department of Anesthesiology and Critical Care, University of Pennsylvania Health System (2016)

Boards, Advisory Committees, Professional Organizations

  • Diplomate, American Board of Anesthesiology (2018 - Present)
  • Diplomate, National Board of Echocardiography (2018 - Present)
  • Member, Society of Cardiovascular Anesthesiologists (2016 - Present)

Professional Education

  • Fellowship, Stanford University Hospital, Cardiothoracic Anesthesiology (2017)
  • Residency, Hospital of the University of Pennsylvania, Anesthesiology (2016)
  • MD, University of Pennsylvania School of Medicine (2012)
  • BA, University of Pennsylvania (2008)


All Publications

  • First lung and kidney multi-organ transplant following COVID-19 Infection. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Guenthart, B. A., Krishnan, A., Alassar, A., Madhok, J., Kakol, M., Miller, S., Cole, S. P., Rao, V. K., Acero, N. M., Hill, C. C., Cheung, C., Jackson, E. C., Feinstein, I., Tsai, A. H., Mooney, J. J., Pham, T., Elliott, I. A., Liou, D. Z., La Francesca, S., Shudo, Y., Hiesinger, W., MacArthur, J. W., Brar, N., Berry, G. J., McCarra, M. B., Desai, T. J., Dhillon, G. S., Woo, Y. J. 2021


    As the world responds to the global crisis of the COVID-19 pandemic an increasing number of patients are experiencing increased morbidity as a result of multi-organ involvement. Of these, a small proportion will progress to end-stage lung disease, become dialysis dependent, or both. Herein, we describe the first reported case of a successful combined lung and kidney transplantation in a patient with COVID-19. Lung transplantation, isolated or combined with other organs, is feasible and should be considered for select patients impacted by this deadly disease.

    View details for DOI 10.1016/j.healun.2021.02.015

    View details for PubMedID 34059432

  • Management of Patients on Mechanical Circulatory Assist Devices During Noncardiac Surgery. International anesthesiology clinics Rao, V. K., Tsai, A. 2018; 56 (4): e1?e27

    View details for DOI 10.1097/AIA.0000000000000205

    View details for PubMedID 30204602

  • Irregular Respiration as a Marker of Wakefulness During Titration of CPAP SLEEP Ayappa, I., Norman, R. G., Whiting, D., Tsai, A. W., Anderson, F., Donnely, E., Silberstein, D. J., Rapoport, D. M. 2009; 32 (1): 99?104


    Regularity of respiration is characteristic of stable sleep without sleep disordered breathing. Appearance of respiratory irregularity may indicate onset of wakefulness. The present study examines whether one can detect transitions from sleep to wakefulness using only the CPAP flow signal and automate this recognition.Prospective study with blinded analysisSleep disorder center, academic institution.74 subjects with obstructive sleep apnealhypopnea syndrome (OSAHS) INTERVENTIONS: n/a.74 CPAP titration polysomnograms in patients with OSAHS were examined. First we visually identified characteristic patterns of ventilatory irregularity on the airflow signal and tested their relation to conventional detection of EEG defined wake or arousal. To automate recognition of sleep-wake transitions we then developed an artificial neural network (ANN) whose inputs were parameters derived exclusively from the airflow signal. This ANN was trained to identify the visually detected ventilatory irregularities. Finally, we prospectively determined the accuracy of the ANN detection of wake or arousal against EEG sleep/wake transitions. A visually identified irregular respiratory pattern (IrREG) was highly predictive of appearance of EEG wakefulness (Positive Predictive Value [PPV] = 0.89 to 0.98 across subjects). Furthermore, we were able to automate identification of this irregularity with an ANN which was highly predictive for wakefulness by EEG (PPV 0.66 to 0.86).Despite not detecting all wakefulness, the high positive predictive value suggests that analysis of the respiration signal alone may be a useful indicator of CNS state with potential utility in the control of CPAP in OSAHS. The present study demonstrates the feasibility of automating the detection of IrREG.

    View details for Web of Science ID 000262075600016

    View details for PubMedID 19189784

    View details for PubMedCentralID PMC2625330

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