School of Medicine
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Professor of Pediatrics (Pulmonary Medicine) and, by courtesy, of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly Interests My research interests have centered on the inflammatory responses that lead to airway disease in Cystic Fibrosis (CF) and the metabolic factors that contribute to CF lung disease progression. Current efforts are focused on the understanding of the early events that drive the development of lung disease through the study of infants with CF identified by newborn screening. This includes the development of new diagnostic tools that permit the early detection of lung disease manifestations.
Richard B. Moss
Professor of Pediatrics at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly Interests Immunopathogenesis of chronic airways diseases of childhood, including cystic fibrosis, asthma, allergic aspergillosis and bronchopulmonary dysplasia. Translational research: early clinical trials in airways disease of childhood, most notably CF, including gene, cytokine and drug therapy. Recent projects focus on development of biomarkers and treatments for allergic fungal lung disease, e.g. inhaled antifungals.
Clinical Assistant Professor, Pediatrics - Pulmonary Medicine
Bio Dr. Okorie is board certified in pediatric pulmonology, sleep medicine and general pediatrics and joined the Division of Pediatric Pulmonary, Asthma and Sleep Medicine in 2018. She obtained her medical degree and Master?s in Public Health at the University of Arizona before going on to a residency and chief residency in pediatrics at Oregon Health & Science University. She completed her fellowship training in both pediatric pulmonary medicine and sleep medicine at Stanford University. She has a passion for medical education and serves as an Associate Program Director for the Pediatric Residency Program at Stanford.
She treats children with a variety of lung diseases, including: asthma, chronic cough, cystic fibrosis, chronic respiratory failure, and chronic lung disease of prematurity. Her additional training in sleep medicine allows her expertise to treat sleep disorders, including: sleep disordered breathing, parasomnias, narcolepsy, restless legs syndrome, and insomnia.
Associate Professor of Pediatrics (Pulmonary) at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly Interests My research interests focus on detection of early and progressive Cystic fibrosis (CF) structural lung disease by utilizing chest CT imaging and CT post-processing methodology. Current research efforts involve utilization of low dose infant & children CT imaging protocols and quantitative airway and air trapping algorithms to evaluate early and progressive CF disease.
Clinical Instructor, Pediatrics - Pulmonary Medicine
Bio Dr. Sinha is board certified in Pediatrics and Sleep Medicine. She completed medical school in Australia and general pediatric training in Australia and USA at Royal Children?s Hospital and University of Chicago at Illinois. Her sleep medicine fellowship was completed at Stanford Hospital. She enjoys working with children of all ages. She manages both behavioral and physiological sleep concerns.
Instructor, Pediatrics - Pulmonary Medicine
Bio Dr. Steffes, a Wisconsin native, completed medical school and pediatric residency at the Medical College of Wisconsin. She then moved to the Bay Area and completed her clinical fellowship in pediatric pulmonary medicine at Stanford University in 2020. Additionally, Dr. Steffes received further post-doctoral training in the laboratories of Dr. Maya Kumar and Dr. David Cornfield, studying the cellular and molecular mechanism driving pulmonary vascular disease. In addition to her role as an Instructor in Pediatrics in the division of Pulmonary Medicine, Dr. Steffes is also completing an advanced clinical fellowship in Pulmonary Hypertension at Lucile Packard Children?s Hospital Stanford. Her clinical work consists of caring for patients with pediatric pulmonary and pulmonary vascular diseases such as pulmonary hypertension, bronchopulmonary dysplasia, interstitial lung disease, respiratory failure, chronic cough and asthma. Her research is focused on the vascular changes seen in pulmonary hypertension, more specifically understanding the cellular characteristics of occlusive neointimal lesions, the abnormal cells that block pulmonary blood flow in pulmonary hypertension. In her most recent work, Dr. Steffes identified a subset of healthy vascular smooth muscle cells that are the cell of origin for the pathologic neointimal cells and a specific signaling pathway, that when blocked, inhibits the formation of neointimal lesions.
Dr. Steffes is currently employing advanced single cell sequencing technologies to further understand neointimal cells with the ultimate goal identifying new therapies for pulmonary hypertension, a fatal disease with no known cure.