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Bio

Professional Education


  • Doctor of Philosophy, University of British Columbia (2019)
  • Master of Science, Natl & Capodistrian Univ Of Athens (2013)
  • Bachelor of Science, Natl & Capodistrian Univ Of Athens (2011)

Stanford Advisors


Publications

All Publications


  • Zirconium Catalyzed Hydroaminoalkylation for the Synthesis of alpha-Arylated Amines and N-Heterocycles. Chemistry (Weinheim an der Bergstrasse, Germany) Koperniku, A., Schafer, L. 2021

    Abstract

    We report the zirconium catalyzed hydroaminoalkylation of alkenes with N-aryl- and sterically demanding N-alkyl-alpha-arylated secondary amines using commercially available Zr(NMe2)4. N-phenyl- and N-isopropylbenzylamine are used as amine substrates to establish the alkene substrate scope. Exclusively linear products are obtained in the presence of bulky vinylsilanes. Challenging alpha-heteroarylated amines and functionalized alkene substrates are compatible with this easy to use catalyst, affording a new disconnection strategy for the atom- and step-economic preparation of selectively substituted saturated alpha-arylated heterocycles.

    View details for DOI 10.1002/chem.202100014

    View details for PubMedID 33427338

  • Zirconium Hydroaminoalkylation. An Alternative Disconnection for the Catalytic Synthesis of ?-Arylated Primary Amines J. Am. Chem. Soc. Koperniku, A., Foth, P. J., Sammis, G. M., Schafer, L. L. 2019; 141 (48): 18944-18948
  • The Reaction of N-Trimethylsilyl Substituted Heteroarylamines with Thio- and Oxoesters: An Efficient Protocol to Access Diheteroarylamides, Synthesi Synthesis Koperniku, A., Zamiri, M., Grierson, D. S. 2019; 51 (08): 1779-1790
  • Mono- and Difluorination of Benzylic Carbon Atoms Eur. J. Org. Chem. Koperniku, A., Liu, H., Hurley, P. B. 2016; 5: 871-886
  • 4-(1-Adamantyl)phenylalkylamines with Potential Antiproliferative Activity Lett. Org. Chem. Koperniku, A., Foscolos, A. S., Papanastasiou, I., Foscolos, G. B., Tsotinis, A., Schols, D. 2016; 13 (3): 171-176
  • Synthesis and Trypanocidal Action of New Adamantane Substituted Imidazolines MedChemComm Koperniku, A., Papanastasiou, I., Foscolos, G. B., Tsotinis, A., Taylor, M. C., Kelly, J. M. 2013; 4: 856-859

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