Robert Huang

Assistant Professor of Medicine (Gastroenterology and Hepatology)

Bio

I am a gastroenterologist who seeks to use both science and clinical practice to improve the prevention, diagnosis, and therapy of digestive malignancies. My clinical practice is focused on the use of advanced endoscopic imaging procedures (such as endoscopic ultrasound, chromoendoscopy, and confocal endomicroscopy) to improve cancer detection, and therapeutic endoscopic procedures to remove or destroy cancer and precancerous lesions.

My research is aimed at improving digestive cancer outcomes and reducing cancer disparities through data science, cohort building, and biomarker development. My research is currently supported by an NIH Mentored Career Development Award (K08CA252635). I have formal pre-doctoral (NIH-Clinical Research Training Program) and post-doctoral (T32DK007056) training in epidemiology and clinical research.

Clinical Focus

Gastroenterology
ERCP, endoscopic ultrasound, luminal stenting, small bowel endoscopy
gastric cancer, gastric intestinal metaplasia and premalignant lesions

Academic Appointments

Assistant Professor - University Medical Line, Medicine - Gastroenterology & Hepatology
Member, Stanford Cancer Institute

Honors & Awards

Fellow, American Society of Gastrointestinal Endoscopy (ASGE) (2024)
Diversity Investigator Award, Stanford Department of Medicine (2021)
Health Disparities Research Institute Scholar, NIMHD (2021)
K08 Mentored Career Development Award (CA252635), National Cancer Institute (2021)
Resource Center for Minority Aging Career Development Grant, National Institutes of Aging (P30AG0059304) / Rutgers University (2021)
Young Physician Leadership Scholar, American College of Gastroenterology (2020)
North American International Training Grant, American College of Gastroenterology (2019)
Top Reviewer, Annals of Internal Medicine (2018)
Chief Fellow, Division of Gastroenterology, Stanford University (2016-2017)
T32 Institutional Research Training Grant (DK007056), National Institutes of Health (2015-2017)
William G. Anlyan Scholarship, Duke University School of Medicine (2010)
NIH-Clinical Research Training Program (CRTP), National Institutes of Health (2009-2010)
Harvard College Scholar, Harvard College (2003-2005)

Projects

The Stanford Gastric Precancerous Conditions Study (GAPS)

The goal of the Stanford GPC Study is to 1) identify non-invasive markers to identify patients at high risk for advanced GPCs and 2) develop molecular risk stratification models to predict which patients with advanced GPCs will progress onto gastric cancer. We are seeking to recruit subjects between the ages of 30 to 84 with 1) a personal history of GPC (either intestinal metaplasia or gastric atrophy) 2) a family history of gastric cancer or 3) dyspepsia or abdominal pain. The research involves a brief questionnaire, blood draw, saliva specimen, and gastric biopsies. We hope that through this research we will develop molecular tests which will improve the early detection of gastric cancer.

Location

Stanford, CA

Professional Education

Fellowship: Stanford University Gastroenterology Fellowship (2017) CA
Residency: Stanford University Internal Medicine Residency (2014) CA
Board Certification: American Board of Internal Medicine, Gastroenterology (2018)
Board Certification: American Board of Internal Medicine, Internal Medicine (2014)
Residency, Stanford Hospital and Clinics, Internal Medicine (2014)
Medical Education: Duke University School of Medicine (2011) NC
M.D., Duke University School of Medicine (2011)
A.B., Harvard College, Biochemical Sciences, magna cum laude (2007)

Contact

Administrative Contact Michelle Hang Administrative Associate mhang1@stanford.edu

Clinical (Primary)

This is the primary clinic for this clinical provider. For additional clinical locations and information, please visit the link(s) listed below in the 'Additional Clinical Info' section.

Medicine 300 Pasteur Dr Rm JC007 Stanford CA 94305 Tel: (650) 725-5071 Fax: (650) 725-8381

Additional Clinical Info

Stanford Health Care

Current Research and Scholarly Interests

Epidemiology
Epidemiology of gastric cancer
Racial and ethnic disparities in gastric cancer
Gastric intestinal metaplasia and other precancerous lesions
Molecular marker development
Microbiome

Clinical Trials

The GAstric Precancerous Conditions Study Recruiting
More
Gastric cancer afflicts 27,000 Americans annually and carries a dismal prognosis. One reason for poor outcomes is late diagnosis, as the majority of gastric cancers in the United States are diagnosed at a relatively advanced stage where curative resection is unlikely. Gastric intestinal metaplasia (GIM) is a precancerous change of the stomach which increases risk for subsequent gastric cancer multiple-fold. The Gastric Precancerous Conditions Study (GAPS) is an observational study with two over-arching objectives: 1) improve the non-invasive identification of patients with GIM, and 2) develop biological markers to predict the subset of GIM which will progress onto gastric cancer. To achieve Aim 1, a case-control study (N=300 pairs) matching cases of GIM with age-/gender-matched controls will be recruited form the population of subjects undergoing clinically-indicated endoscopy. Determination of gastric pathology will be made by two, independent gastrointestinal pathologists. At time of endoscopy, a detailed clinical questionnaire is administered by face-to-face interview. Saliva and blood is collected prior to endoscopy. At time of endoscopy, protocoled clinical biopsies (per Revised Sydney Protocol) as well as additional research specimens are collected. Scoring of GIM will be performed based on the Operative Link for GIM scoring system. To achieve Aim 2, patients with histologically-confirmed GIM (N=300) will be followed longitudinally. Biennial endoscopic surveillance will be performed, with repeat biopsies, specimen collection, and histologic scoring. Progression of GIM will be defined as upstaging of GIM score, or development of either dysplasia or carcinoma on any biopsy.

Lead Sponsor
- Stanford University
Stanford Investigators
- Robert Huang
- Joo Ha Hwang, MD, PhD
View full details
The Gastric Cancer Foundation: A Gastric Cancer Registry Recruiting
More
The Gastric Cancer Registry will combine data acquired directly from patients with gastric cancer; with a family history of gastric cancer in a first or second degree relative; or persons with a known germline mutation in their CDH1 (E-Cadherin) gene via an online questionnaire with genomic data obtained from saliva, blood and tissue samples. The purpose of this registry is to gain better understanding of the causes of gastric cancer, both environmental and genetic; whether certain genomic data can predict outcomes of treatment and survival.

Lead Sponsor
- Stanford University
Stanford Investigators
View full details

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