Current Research and Scholarly Interests
My long-term research interests involve understanding the molecular mechanisms of age-dependent neurodegenerative diseases. My academic and research training were focused in protein misfolding, aging and proteostasis. The focus of my postdoctoral research at Stanford University is understanding the molecular pathobiology of Parkinson’s disease, specifically related to mutations in the LRRK2 gene. My main projects include:
1) Exploring the role of endolysosomal proteins in LRRK2-related PD pathogenesis, especially the malfunctions in disease conditions.
2) Understanding the molecular crosstalks participating in the cognitive impairment associated with Parkinson's and Alzheimer's Disease
3) Developing a reliable imaging technique for analyses of post-mortem brain tissues from Parkinson's Disease patients, which would be key in revealing new molecular pathways and therapeutic opportunities.