Yi Miao

Basic Life Research Scientist, Molecular and Cellular Physiology

All Publications

Publications (18)

All Publications (18)
Journal Articles (18)

Profiles With Related Publications

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Axel Brunger

Professor of Molecular and Cellular Physiology, of Neurology, of Photon Science and, by courtesy, of Structural Biology
Research Interests
One of Axel Brunger's major goals is to decipher the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, combined with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.

205 Total Publications
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Lynette Cegelski

Professor of Chemistry

73 Total Publications
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Martha S. Cyert

Dr. Nancy Chang Professor
Research Interests
The Cyert lab is identifying signaling networks for calcineurin, the conserved Ca2+/calmodulin-dependent phosphatase, and target of immunosuppressants FK506 and cyclosporin A, in yeast and mammals. Cell biological investigations of target dephosphorylation reveal calcineurin’s many physiological functions. Roles for short linear peptide motifs, or SLiMs, in substrate recognition, network evolution, and regulation of calcineurin activity are being studied.

70 Total Publications
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Alexander Eric Doan

MD Student with Scholarly Concentration in Molecular Basis of Medicine, expected graduation Spring 2025

4 Total Publications
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Michael Fischbach

Liu (Liao) Family Professor

149 Total Publications
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Judith Frydman

Donald Kennedy Chair in the School of Humanities and Sciences and Professor of Genetics
Research Interests
The long term goal of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.

172 Total Publications
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Chris Garcia

Younger Family Professor and Professor of Structural Biology
Research Interests
Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology. We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.

349 Total Publications
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Kip E. Guja, MD PhD

Clinical Instructor, Radiology - Rad/Nuclear Medicine
Clinical Focus
PET Imaging, Theragnostics, Diagnostic Radiology, Pediatric Radiology, Nuclear Radiology

39 Total Publications
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Diptarka Hait

Postdoctoral Scholar, Chemistry

41 Total Publications
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Pehr Harbury

Associate Professor of Biochemistry
Research Interests
Scientific breakthroughs often come on the heels of technological advances; advances that expose hidden truths of nature, and provide tools for engineering the world around us. Examples include the telescope (heliocentrism), the Michelson interferometer (relativity) and recombinant DNA (molecular evolution). Our lab explores innovative experimental approaches to problems in molecular biochemistry, focusing on technologies with the potential for broad impact.

59 Total Publications
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Possu Huang

Assistant Professor of Bioengineering

58 Total Publications
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Ted Jardetzky

Professor of Structural Biology
Research Interests
The Jardetzky laboratory is studying the structures and mechanisms of macromolecular complexes important in viral pathogenesis, allergic hypersensitivities and the regulation of cellular growth and differentiation, with an interest in uncovering novel conceptual approaches to intervening in disease processes. Ongoing research projects include studies of paramyxovirus and herpesvirus entry mechanisms, IgE-receptor structure and function and TGF-beta ligand signaling pathways.

190 Total Publications